Detalhe da pesquisa
1.
IL7 increases targeted lipid nanoparticle-mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation.
Proc Natl Acad Sci U S A
; 121(13): e2319856121, 2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38513098
2.
Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
Mol Ther
; 32(5): 1344-1358, 2024 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38454606
3.
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism.
Small
; 20(11): e2304378, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38072809
4.
Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs.
Mol Ther
; 29(11): 3293-3304, 2021 11 03.
Artigo
Inglês
| MEDLINE | ID: mdl-34091054
5.
AKT3 Gene Transfer Promotes Anabolic Reprogramming and Photoreceptor Neuroprotection in a Pre-clinical Model of Retinitis Pigmentosa.
Mol Ther
; 27(7): 1313-1326, 2019 07 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31043342
6.
Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system.
Mol Ther Nucleic Acids
; 35(2): 102175, 2024 Jun 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38576454
7.
Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects.
bioRxiv
; 2024 Apr 18.
Artigo
Inglês
| MEDLINE | ID: mdl-38659905
8.
In vivo hematopoietic stem cell modification by mRNA delivery.
Science
; 381(6656): 436-443, 2023 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37499029
9.
Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke.
bioRxiv
; 2023 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37398465
10.
CAR T cells produced in vivo to treat cardiac injury.
Science
; 375(6576): 91-96, 2022 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34990237
11.
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
J Control Release
; 344: 50-61, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34953981
12.
Identification of a novel pathogenic missense mutation in PRPF31 using whole exome sequencing: a case report.
Br J Ophthalmol
; 103(6): 761-767, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-30030392
13.
CRISPR Activation Enhances In Vitro Potency of AAV Vectors Driven by Tissue-Specific Promoters.
Mol Ther Methods Clin Dev
; 13: 380-389, 2019 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-31024980